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Publications

Economic Outcomes of a Precision Medicine Blood Test To Assess Obstructive Coronary Artery Disease: Results from the PRESET Registry
Ladapo JA, Budoff MJ, Azarmina P, et al.
Managed Care. June 2018.

Utility of a Precision Medicine Test in Elderly Adults with Symptoms Suggestive of Coronary Artery Disease
Ladapo JA, Budoff MJ, Sharp D, et al.
J Am Geriatr Soc. 2018;66(2):309-315.

The Expressed Genome in Cardiovascular Diseases and Stroke: Refinement, Diagnosis, and Prediction: A Scientific Statement From the American Heart Association.
Musunuru K, Ingelsson E, Fornage M, et al.
Circ Cardiovasc Genet. 2017;10(4):e1-e25.

Clinical Utility of a Precision Medicine Test Evaluating Outpatients with Suspected Obstructive Coronary Artery Disease
Ladapo JA, Budoff M, Sharp D, et al.
Am J Med. 2017;130(4):482.e11-482.e17

An age- and sex-specific gene expression score is associated with revascularization and coronary artery disease: Insights from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial
Voora D, Coles A, Lee K, et al.
Am Heart J. 2017;184:133-140.

A Novel Diagnostic Approach for Evaluating Suspected Coronary Artery Disease.
Boden WE.
Am J Med. 2016;129(6):557-559.

Impact of Exercise Stress Testing on Diagnostic Gene Expression in Patients With Obstructive and Nonobstructive Coronary Artery Disease.
Filsoof DM, Safford RE, Newby K, et al.
Am J Cardiol. 2015 May 15;115(10):1346-50.

Enhanced Assessment of Chest Pain and Related Symptoms in the Primary Care Setting Through the Use of a Novel Personalized Medicine Genomic Test: Results From a Prospective Registry Study
Ladapo JA, Lyons H, Yau M, et al.
Am J Med Qual. 2015;30(4):345-352.

Use of a Blood Test Incorporating Age, Sex, and Gene Expression Influences Medical Decision-Making in the Evaluation of Women Presenting with Symptoms Suggestive of Obstructive Coronary Artery Disease: Summary Results From Two Ambulatory Care Studies in Primary Care.
Ladapo JA, Herman L, Weiner BH, et al.
Menopause. 2015;22(11):1224-1230

Biological and Analytical Stability of a Peripheral Blood Gene Expression Score for Obstructive Coronary Artery Disease in the PREDICT and COMPASS Studies
Daniels SE, Beineke P, Rhees B, et al.
J Cardiovasc Transl Res. 2014;7(7):615-622.

Utility of a Genomic-based, Personalized Medicine Test in Patients Presenting With Symptoms Suggesting Coronary Artery Disease
Herman L, Froelich J, Kanelos D, et al.
J Am Board Fam Med. 2014;27:258–267.

Economic Utility of a Blood-Based Genomic Test for the Assessment of Patients With Symptoms Suggestive of Obstructive Coronary Artery Disease
Hochheiser LI, Juusola JL, Monane M, et al.
Popul Health Manag. 2014;17(5):287-96.

Cost Effectiveness of a Gene Expression Score and Myocardial Perfusion Imaging For Diagnosis of Coronary Artery Disease
Phelps CE, O’Sullivan AK, Ladapo JA, et al.
Am Heart J. 2014 May;167(5):697-706.

A Peripheral Blood Gene Expression Score is Associated With Atherosclerotic Plaque Burden and Stenosis by Cardiovascular CT-Angiography: Results From the PREDICT and COMPASS Studies
Voros S, Elashoff MR, Wingrove JA, et al.
Atherosclerosis. 2014;233(1):284-290.

Clinical Implications of Referral Bias in the Diagnostic Performance of Exercise Testing for Coronary Artery Disease
Ladapo JA, Blecker S, Elashoff MR, et al.
J Am Heart Assoc. 2013;2(6):e000505.

Use of the Corus CAD Gene Expression Test for Assessment of Obstructive Coronary Artery Disease Likelihood in Symptomatic Non-Diabetic Patients
Vargas J, Lima JAC, Kraus WE, et al.
PLoS Curr. 2013;5: ecurrents.eogt.0f04f6081905998fa92b99593478aeab. Accessed July 2015.

A Peripheral Blood Gene Expression Score is Associated With Plaque Volume and Phenotype by Intravascular Ultrasound With Radiofrequency Backscatter Analysis: Results From the ATLANTA Study.
Joshi PH, Rinehart S, Vazquez G, et al.
Cardiovasc Diagn Ther. 2013;3(1):5-14.

The Clinical Utility of Gene Expression Testing on the Diagnostic Evaluation of Patients Presenting to the Cardiologist with Symptoms of Suspected Obstructive Coronary Artery Disease: Results From the IMPACT (Investigation of a Molecular Personalized Coronary Gene Expression Test on Cardiology Practice Pattern) Trial
McPherson JA, Davis K, Yau M, et al.
Crit Pathw Cardiol. 2013;12(2):37-42

A Blood-Based Gene Expression Test for Obstructive Coronary Artery Disease Tested in Symptomatic Non-Diabetic Patients Referred for Myocardial Perfusion Imaging: The COMPASS Study
Thomas GS, Voros S, McPherson JA, et al.
Circ Cardiovasc Genet. 2013;6(2):154-162.

A Gender-Specific Blood-Based Gene Expression Score for Assessing Obstructive Coronary Artery Disease in Nondiabetic Patients: Results of the Personalized Risk Evaluation and Diagnosis in the Coronary Tree (PREDICT) Trial
A Lansky, MR Elashoff, V Ng, J McPherson, D Lazar, WE Kraus, S Voros, R Schwartz and EJ Topol.
Am Heart J. 2012;164:320-326.

Identification of Factors Contributing to Variability in a Blood-Based Gene Expression Test
MR Elashoff, R Nuttall, PB Beineke, MH Doctolero, M Dickson, AM Johnson, SE Daniels, S Rosenberg and JA Wingrove.
PLoS ONE. 2012;7(7):e40068

Whole Blood Gene Expression Testing for Coronary Artery Disease in Nondiabetic Patients: Major Adverse Cardiovascular Events and Interventions in the PREDICT Trial
Rosenberg S, Elashoff MR, Lieu HD, et al
J Cardiovasc Transl Res. 2012 Jun;5:366-374

Development of a Blood-Based Gene Expression Algorithm for Assessment of Obstructive Coronary Artery Disease in Non-diabetic Patients
MR Elashoff, JA Wingrove, P Beineke, SE Daniels, WG Tingley, S Rosenberg, S Voros, WE Kraus, GS Ginsburg, RS Schwartz, SG Ellis, N Tahirkheli, R Waksman, J McPherson, AJ Lansky and EJ Topol.
BMC Med Genomics.
2011;4:26.

Multicenter Validation of the Diagnostic Accuracy of a Blood-Based Gene Expression Test for Assessing Obstructive Coronary Artery Disease in Nondiabetic Patients
S Rosenberg, M Elashoff, P Beineke, S Daniels, J Wingrove, W Tingley, P Sager, A Sehnert, M Yau, W Kraus, LK Newby, RS Schwartz, S Voros, SG Ellis, N Tahirkheli, R Waksman, J McPherson, A Lansky, ME Winn, NJ Schork, EJ Topol; and for the PREDICT (Personalized Risk Evaluation and Diagnosis in the Coronary Tree) Investigators.
Ann Intern Med.
2010;153:425–434.

Correlation of Peripheral-Blood Gene Expression With the Extent of Coronary Artery Stenosis
JA Wingrove, SE Daniels, AJ Sehnert, W Tingley, MR Elashoff, S Rosenberg, L Buellesfeld, E Grube, LK Newby, GS Ginsburg and WE Kraus.
Circ Cardiovasc Genet.
2008;1(1):31–38.

Lack of Association Between Adrenergic Receptor Genotypes and Survival in Heart Failure Patients Treated With Carvedilol or Metoprolol
AJ Sehnert, SE Daniels, M Elashoff, et al.
J Am Coll Cardiol.
2008;52:644–651.